SE OF ULTRASOUND SCAN TO IDENTIFY PATIENTS AT RISK OF DEVOPING KIDNEY FAILURE IN ICUULTRASOUND SCANS WILL BE CONDUCTED IN SICK PATIENTS IN ICU WHO ARE REQUIRING MEDICATIONS TO MAINTAIN BLOOD PRESSURE. THE PARAMETERS OBSERVED IN SERIAL ULRASOUND SCAN WILL BE CORRELATED WITH RENAL FAILURE

Not Applicable

• Conditions: Health Condition 1: I958- Other hypotension

• Registration Number: CTRI/2020/03/023755
• Lead Sponsor: All India Institute of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Age 18-65 years

Within 24 hours of ICU admission

Acute Circulatory Failure â?? As defined by requirement of Vasoactive agents (in spite of adequate fluid resuscitation) for more than two consecutive hours to target MAP >65 mmHg or to a MAP considered to be optimal by treating physician

Exclusion Criteria

AKI on admission As defined by KDIGO guidelines if preadmission creatinine is available

As per MDRD study calculation if preadmission creatinine is not available

Non-index ICU admission

Poor abdominal echogenicity

Chronic kidney disease as defined eGFR less than 60 ml /min / 1.73m2

On Renal Replacement Therapy, Renal Transplant recipients, Single kidney patients,Renal donors,Known Renal Artery stenosis, Pregnancy, Kidney tumor, Known anatomical kidney abnormality

Suspected Intra-abdominal hypertension, Obstructive uropathy, Urotrauma, Status post â?? Urological or Aortic surgery or Intervention

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To identify if the parameters derived from renal Doppler ultrasound (RRI,PDU and their ratio) measured daily for first three days (initial value and its change over 72 hours) can predict development of Acute Kidney Injury (AKI) as defined by KDIGO criteria nTimepoint: 5 days

Secondary Outcome Measures

Name	Time	Method
Requirement of Renal Replacement Therapy <br/ ><br>Length of ICU stay <br/ ><br>Mortality at 28 days <br/ ><br>Number of days on vasopressor therapy <br/ ><br>Number of days on Mechanical ventilation <br/ ><br>Timepoint: As mentioned above