Effects of Early Exercise in Patients With Moderate to Severe Stroke - a Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- Klas Sandberg
- Enrollment
- 52
- Primary Endpoint
- Change in Modified Rankin Scale (mRS)
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
Purpose: to investigate the efficacy of early exercise in patients with moderate to severe stroke regarding functional outcome and walking ability.
Methods: Patients with medium to severe stroke (NHISS >7) were recruited 24 - 48 hours after stroke onset from two stroke units in Sweden. Both groups received usual care. The intervention group received even 20 minutes bed-cycling 5 days per week with a maximum of 15 sessions. Functional outcome was measured with modified Rankin Scale (mRS) and Barthel index and walking with the 6-minute walking test (6MWT). Measurements were performed pre- and post-intervention (3 weeks), and at 3-months follow-up.
Investigators
Klas Sandberg
Clinical Investigator
Ostergotland County Council, Sweden
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Change in Modified Rankin Scale (mRS)
Time Frame: Baseline 24-48 hours after onset, postintervention 3 weeks after baseline and follow up 3-months after baseline.
Functional Outcome
Secondary Outcomes
- Change in 6-Minutes Walking test (6MWT)(Baseline 24-48 hours after stroke onset, postintervention 3-weeks after baseline and follow up 3-months after baseline.)
- Change in Barthel ADL-Index(Baseline 24-48 hours after stroke onset, postintervention 3-weeks after baseline and follow up 3-months after baseline.)