The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar(Split Mouth Technique)
Trial Snapshot
- Phase
- Phase 1
- Status
- Completed
- Sponsor
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- post operative pain changes
Study Overview
Brief Summary
Evaluating the effectiveness of using a single immediate postoperative intramuscular Dexamethasone injection on pain, swelling, trismus and tissue healing in the first seven days.
Methods: A split mouth technique on 16 patients with bilateral similar impacted mandibular third molar were extracted; one side was given 8mg intramuscular injection of dexamethasone (study group) and the other side wasn't given injection (control group) and compare of the two sides were done in the following seven days.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 15 Years to 40 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •bilateral similar impacted lower third molar
- •willing to do surgical extraction
Exclusion Criteria
- •Patients who are not fulfill the inclusion criteria
- •allergic to dexamethasone
- •who has medical diseases
- •taking any medications
- •pregnant or lactating women
Arms & Interventions
dexamethasone immediate injection postoperatively
intramuscular injection of a single dose 8mg dexamethasone immediate postoperatively after removal of impacted mandibular third molar
Intervention: Dexamethasone (Drug)
Outcomes
Primary Outcomes
post operative pain changes
Time Frame: each participant was seen at 1st, 3rd and 7th post-operative days
measurement of change in pain on visual scale analog from 10 to 1 , 10 mean the worst pain and 1 is least pain
Change in post operative swelling
Time Frame: each participant was seen at 1st, 3rd and 7th post-operative days
The swelling was measured between two points marked on skin in millimeters using ruler
Post operative Change in mouth opening
Time Frame: each participant was seen at 1st, 3rd and 7th post-operative days
The distance between upper and lower incisors was measured in millimeters using ruler
Secondary Outcomes
- Tissue healing(Healing was assessed on the 7th postoperative day)
Investigators
Yassir R. Al-khannaq
lecturer Dr.
University of Baghdad