Kinematic Analysis in Stroke Patients Using Microsoft Kinect and Akira Software: Kinect-Akira Movement Study

• Conditions: Stroke

• Registration Number: NCT04464863
• Lead Sponsor: Instituto de Investigación Hospital Universitario La Paz

Brief Summary

In this prospective, unicentric, case-control study, the main aim is to analyze joint movement and walking patterns in patients with acute stroke with a marker-free motion capture system. Case group: Stroke patients who fulfill the inclusion criteria are invited to participate in the study during admission. The evaluation consists of a workout designed by expert rehabilitation physicians and neurologists that is performed by the patient in front of the Microsoft Kinect camera. The custom-built software Akira record the joint angles of body trunk and upper limbs during the workout. The kinematic data will be analyzed with a machine learning algorithm that classifies the participant according to the kinematic data in normal movement or impaired movement (with the degree of impairment) by age decade. Control group: healthy participants (without neurological or osteomuscular diseases) matched by age and sex with cases 1:1. The correlation between kinematic and clinical scales (NIHSS) and functional scales (modified Rankin Scale) will be analyzed. A secondary objective will be to analyze the predictive value of the kinematic measurements with the functional outcome at three months

Detailed Description

Not available

Study Timeline

• Study Start: 2020-01-29
• Status Verified: 2020-04
• Study First Submitted: 2020-06-11
• Study First Submitted QC: 2020-07-06
• Last Update Submitted: 2020-07-06
• Study First Posted: 2020-07-09
• Last Update Posted: 2020-07-09
• Primary Completion: 2021-01-29
• Study Completion: 2021-06-29

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• Acute Stroke patients (within the first week of index stroke)
• Neurological deficit present at the moment of the evaluation.
• Informed consent signed.

Exclusion Criteria

• Clinical instability
• Aphasia or cognitive decline that prevents the understanding of the workout.
• Refuse to participate
• Previous neurological or osteomuscular conditions.
• Previous conditions with less than 3 months of expectancy of life.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Kinematic metrics: movement acceleration	The change between the first week of index stroke (acute phase) and at 3 months after index stroke	The kinect camera together with the software Akira will be used to automatically measure the acceleration of the following movements: shoulder abduction and shoulder flexion.
Kinematic metrics: join angles	The change between the first week of index stroke (acute phase) and at 3 months after index stroke	The kinect camera together with the software Akira will be used to automatically measure the degree angle of the following body joints: shoulder in abduction, shoulder inflexion, elbow in extension and in flexion and the angle formed by the forearm and the trunk with the shoulder in abduction.
Kinematic metrics: movement pattern	The change between the first week of index stroke (acute phase) and at 3 months after index stroke	The kinect camera together with the software Akira will be used to automatically measure the pattern of the following movements: trunk oscillation during standing position and during walking; and trunk oscillation during seating position with opened and closed eyes.

Secondary Outcome Measures

Name	Time	Method
Relationship of kinematic measures with the degree of disability after stroke.	At 3 months after the index stroke	Correlation between the kinematic metrics described before (joint angles, movement acceleration and movement pattern) and the degree of disability, measured y the modified Rankin scale. The modified Rankin Scale (mRS) is a extensively use scale to measure dependency after stroke. The minimum value is 0 (no sequels or disability) and the maximum value is 6 (dead). The lower the score in the scale, the better is the outcome.

Trial Locations

Locations (1)

La Paz University Hospital, IdiPAZ; 🇪🇸 Madrid, Spain