A Study to understand the importance of computer software to identify the eye diseases
- Conditions
- Health Condition 1: H350- Background retinopathy and retinalvascular changes
- Registration Number
- CTRI/2022/06/043171
- Lead Sponsor
- Google LLC
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1) Able to complete adequate or reliable image acquisitions in one or both eyes.
2) Diagnosis of Primary Open Angle Glaucoma (POAG) or Primary Angle Closure Glaucoma
(PACG) based on IOP, Fundus photographs or OCT scans changes showing Notch, Rim
loss, Disc hemorrhage, Nerve Fiber Layer defect, Peripapillary atrophy and Visual Field
defects.
3) Diagnosis of retinal pathologies (DR, AMD, vascular occlusions, macular hole, epiretinal
membrane, retinal detachment, hypertensive retinopathy, disc edema, posterior uveitis)
based on structural changes seen in Fundus or Ultra widefield fundus photographs or OCT
or OCTA.
1) History of trauma or injury to the eye/ symptomatic inflamed eyes
2) Significant media opacity that precludes acquisition of images.
3) Any physical disability which will preclude the patients from performing necessary study
investigations
4) Pregnant and Nursing women
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Successful enrollment of participants and prospective collection ocular images, clinical exam <br/ ><br>findings and blood tests providing a robust ground truth to train and validate a deep learning <br/ ><br>algorithm that can identify novel signals - for example systemic disease - and detect or predict <br/ ><br>progression of ocular pathologies identified in the studyTimepoint: 24 months
- Secondary Outcome Measures
Name Time Method To identify novel signals in retinal imaging that may predict early signs of glaucoma, retinal pathology as well as its systemic associationTimepoint: 24 months
Related Research Topics
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