跳至主要内容
临床试验/NCT05213949
NCT05213949招募中不适用

An Observational Study of Risk Factors and Long-term Prognosis of Patients With Pyogenic Liver Abscess in the "Real-world"

Nanfang Hospital, Southern Medical University1 个研究点 分布在 1 个国家目标入组 160 人开始时间: 2022年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
160
试验地点
1
主要终点
Proportion and causes of deaths within 2 years of discharge from hospital

研究概览

简要总结

Pyogenic liver abscess is one of the most common visceral abscesses, its incidence is increasing worldwide. According to the previous literature, the mortality rate of pyogenic liver abscess is as high as 31% and become a serious social health problem. However, the data of prospective observational real-world studies are scarce and no relevant research of the liver histological change has been reported, so the long-term prognosis and the risk factors for pyogenic liver abscess are still unknown. Patients will be followed up prospectively for a period of 2 years and observed clinical prognosis (all-cause mortality, the recurrence rate, and the rehospitalization rate). The investigators will investigate the predictive value of clinical risk factors for clinical prognosis and establish clinical prediction models to predict the long-term prognosis of pyogenic liver abscesses.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients older than 18 years of age;
  • Irrespective of gender;
  • Symptomatic patients of liver abscess confirmed with radiology imaging, either by ultrasonography or computed tomography scan.

排除标准

  • Patients <18 years old;
  • Pregnancy at presentation.

结局指标

主要结局

Proportion and causes of deaths within 2 years of discharge from hospital

时间窗: 2 years

Define the proportion and causes of deaths within 2 years of discharge from hospital for patients admitted to the Department for pyogenic liver abscesses.

Proportion and causes of re-hospitalization within 2 years of discharge from hospital

时间窗: 2 years

Define the proportion and causes of re-hospitalization within 2 years of discharge from hospital for patients admitted to the Department for pyogenic liver abscesses.

次要结局

  • The recurrence rate of pyogenic liver abscess(2 years)
  • The number of participants with Histological Change in the Liver(2 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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