CTRI/2013/11/004178Other4 期
Comparing the efficacy of intravenous Levetiracetam versus intravenous Valproate in the management of refractory status epilepticus in children : a randomised trial
试验速览
- 阶段
- 4 期
- 状态
- Other
- 发起方
- pgimer
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Children aged 2 to 12 years old of either sex with ongoing clinical seizures(clonic, tonic, tonic clonic, myoclonic, focal or generalized)
- •Clinical seizures despite use of one or more doses of benzodiazepines (IV, IN, Buccal) and IV Phenytoin of 30 mg/kg or includes those who respond to initial doses (30 mg/kg ) of phenytoin but have recurrence within 6 hours of drug administration
排除标准
- •Non-convulsive status epilepticus
- •. Known or suspected cases of neurometabolic or mitochondrial disorders
- •Acute or chronic liver or kidney disease
- •Head injury or neurosurgery in the past one month.
- •Active or recent hemorrhage from any site
- •Documented platelet count <50,000, or INR >2
- •Known or suspected allergy or intolerance to either valproate or levetiracetam
- •Patients of epilepsy already on LEV( >20mg/kg/day) or VPA( >20mg/kg/day)
研究者
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