跳至主要内容
临床试验/NCT04718571
NCT04718571已完成不适用

Nontuberculous Mycobacteria Identified in Clinical Samples in the Geneva Area Over a Period 2015-2020

University Hospital, Geneva1 个研究点 分布在 1 个国家目标入组 231 人开始时间: 2020年8月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
231
试验地点
1
主要终点
Identify nontuberculous mycobacteria species

研究概览

简要总结

Prevalence of NTM diseases has been increasing regularly over the past 30 years in industrialized countries Although NTM are identified worldwide, there are important geographical disparities as to the relative prevalence of NTM species There are no data covering the ecology of NTM in Switzerland. Because of the progressive increase in NTM clinical cases in area Geneva(as noted in other industrialized countries), reporting the specific NTM distribution is important and relevant. In this study, the investigators aimed to: 1/ describe the relative prevalence of NTM species in clinical samples analyzed in the Geneva area, covering ca 500'000 inhabitants over a 5-year period; 2/ determine how many culture positive patients were treated; and 3/ specify the clinical sites involved.

详细描述

This study was performed in the Geneva University Hospitals (HUG), a 2008-bed complex providing care for a population of ca. 500'000 inhabitants. All clinical samples sent for microbiological analysis within HUG are treated by the Bacteriology Laboratory of Geneva University Hospitals. An online database is kept up-to-date and includes all samples processed by the laboratory. The investigators performed a comprehensive analysis of all clinical samples included in this database over a 5-year period (2015-2020). This report focuses only on positive results for nontuberculous mycobacteria (NTM).The following items were recorded: age, gender, BMI whenever available, site of infection (when pulmonary: description of main radiological abnormalities), presence and type of immunosuppression, relevant pulmonary and non-pulmonary comorbidities, results of microscopy, and NTM species identified. The investigators also recorded whether the patient was treated for the identified NTM or not and if a susceptibility profile had been determined (this is not routinely performed and must be requested by the clinician).

The study protocol was approved by their local ethics committee

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Identify nontuberculous mycobacteria species

时间窗: 2015-2020

Results of microscopy (positive or negative smear examination), and NTM species were identified (Rapidly or slow growing mycobacteria)

次要结局

  • Baseline characteristics of patients(2015-2020)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jean-Paul Janssens

Professor Jean-Paul Janssens

University Hospital, Geneva

研究点 (1)

Loading locations...

相似试验

An Ecological Analysis of Nontuberculous... | 临床试验