Prone position in COVID-19 patients effect peripapillary retinal nerve fiber layer thickness and ganglion cell layer thickness

Completed

• Conditions: recovery Covid-19 patients who recieved Prone position; Covid-19; Prone position

• Registration Number: TCTR20220930001
• Lead Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-01-01
• Study Start: 2022-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 61

Inclusion Criteria

1. first COVID-19 diagnosis confirmed by a positive RT-PCR test via nasopharyngeal swab
2. recovered from COVID-19 (2-4 weeks following negative RT-PCR)
3. tested at Siriraj Hospital during 1 September 2021 to 1 January 2022.

Exclusion Criteria

1. ophthalmic condition influencing p-RNFL and m-GCIPL thickness: abnormalities of the congenital optic nerve head, glaucoma, macular disease, uveitis, retinal vascular disorders, myopia with refractive error exceeding 4 diopters, previous intraocular surgery, cataracts, intraocular pressure more than 21 mmHg
2. neurological or systemic conditions influencing p-RNFL and m-GCIPL thickness, such as Alzheimer, diabetes mellitus, Parkinson, or multiple sclerosis
3. clinical status instabilities which presented difficulties in the investigation
4. patients unable to cooperate or remain seated for long periods

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
peripapillary retinal nerve fiber layer thickness at 1,3,and 6 month after recovery Cirrus OCT

Secondary Outcome Measures

Name	Time	Method
ganglion cell layer thickness at 1,3,and 6 month after recovery Cirrus OCT