Pain relief after laparoscopic procedure
Phase 1
- Conditions
- Health Condition 1: null- ASA Grade I and IIHealth Condition 2: K802- Calculus of gallbladder without cholecystitis
- Registration Number
- CTRI/2018/05/013557
- Lead Sponsor
- Govt Medical College Amritsar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. All patients of 18 - 65 years of either sex
2. All ASA grade I and II admitted in the Surgery department.
3. Patients posted for laparoscopic cholecystectomy surgery under general anaesthesia
Exclusion Criteria
Pregnant and lactating women
Patients with morbid obesity i.e. BMI of 35 Kg/m2.
Patients on psychotropic or adrenergic drugs
Refusal by patient to enlist in study
â??Patients with chronic pain syndrome.
â??History of previous abdominal surgery.
â??Patients in whom conversion to open cholecystectomy is done for any reason.
Allergy to study drug.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To study the post-operative analgesic effect of 0.25% levobupivacaine plus dexmedetomidine with 0.25% ropivacaine plus dexmedetomidine with Normal Saline (Control Group) following intra-peritoneal instillation in laparoscopic cholecystectomy. <br/ ><br>2.Duration of postoperative analgesia (hours). <br/ ><br>3.To assess the need of rescue analgesics in post-operative period in all the groups. <br/ ><br>Timepoint: 8 hours <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1.Haemodynamic changes. <br/ ><br>2.Any side effects or complications (confusion, dizziness, auditory and visual disturbances, convulsions, hypertension and cardiovascular collapse, tachycardia, arrthymias and respiratory depression). <br/ ><br> <br/ ><br>Timepoint: 48 hours