Evaluation of Postural Effects on Multiple-breath-washout Derived Lung Function Parameters

• Conditions: Pulmonary Disease; Pulmonary Healthy Controls
• Interventions: Device: multiple breath washout test (MBW)

• Registration Number: NCT02826239
• Lead Sponsor: Universitätsmedizin Mannheim

Brief Summary

The investigators aim to evaluated the effect of postural changes on novel lung function parameters derived from multiple-breath-washout.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02
• Study First Submitted: 2016-06-30
• Study First Submitted QC: 2016-07-05
• Study First Posted: 2016-07-07
• Status Verified: 2020-03
• Last Update Submitted: 2020-03-23
• Last Update Posted: 2020-03-24
• Primary Completion: 2020-12
• Study Completion: 2020-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• patients with and without known pulmonary disease

Exclusion Criteria

• pregnancy
• inability to participate

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
pulmonary disease	multiple breath washout test (MBW)	patients with known or suspected pulmonary disease
pulmonary healthy controls	multiple breath washout test (MBW)	patients without known pulmonary disease

Primary Outcome Measures

Name	Time	Method
change of lung clearance index (LCI) as determined by multiple breath washout	60 minutes

Secondary Outcome Measures

Name	Time	Method
repeatability of lung clearance index (LCI)	60 minutes

Trial Locations

Locations (1)

Universitätsmedizin Mannheim; 🇩🇪 Mannheim, Germany