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临床试验/CTRI/2025/02/080868
CTRI/2025/02/080868尚未招募不适用

Analysis of body fat distribution in different stages of chronic kidney disease

Sriman M1 个研究点 分布在 1 个国家目标入组 125 人开始时间: 2025年3月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
125
试验地点
1
主要终点
Body composition Analyser

研究概览

简要总结

Participant recruitment begins with identifying eligible individuals from the department and conducting preliminary screenings based on set criteria. Baseline data, such as demographics and clinical history, will be collected, followed by anthropometric measurements using standardized equipment. Body composition analysis will be performed using a bioelectrical impedance analyzer, ensuring participants adhere to pre-assessment guidelines like fasting and abstaining from exercise or caffeine. Muscle strength will be measured using a hand dynamometer, with two trials for each hand, recording the highest value. Subcutaneous fat will be assessed with skinfold calipers, averaging three measurements at specific anatomical sites. The 4-meter walking speed test will evaluate physical function, conducted twice to record the best time. Fatigue will be assessed using the Fatigue Severity Scale (FSS) questionnaire, and overall quality of life will be measured using the Kidney Disease Quality of Life (KDQOL) questionnaire, with participants supported as needed for accuracy and completeness. Both muscle mass and strength are crucial predictors of outcomes in CKD patients, who often experience catabolic protein-energy wasting. This study seeks to determine the prevalence of reduced muscle mass and strength across different CKD stages. The observed variations in muscle mass and physical capacity may influence physical activity, fatigue, and overall quality of life, which will be assessed using validated questionnaires.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • Different stages in chronic kidney disease, ambulatory male or female.

排除标准

  • Clinical signs of acute infection, Acute cancer or Liver dysfunction at time of evaluation, Severe heart failure, Amputated limbs.

结局指标

主要结局

Body composition Analyser

时间窗: Baseline

次要结局

  • Hand Grip Strength, Skinfold Measurements, 4 Metre walking speed, Fatigue Severity Score, Kidney Disease Quality Of Life Measurement(Baseline)

研究者

发起方
Sriman M
申办方类型
Other [nil]
责任方
Principal Investigator
主要研究者

Sriman M

Sri Ramachandra Institute of Higher Education and Research

研究点 (1)

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