Comparing Effects of Beetroot Juice and Mediterranean Diet on Liver Enzymes and Sonography in Patients With Non-Alcoholic Fatty Liver Disease (NAFLD): A Randomized Control Trials
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 180
- 试验地点
- 2
- 主要终点
- Beetroot juice has role in reduce liver enzymes
研究概览
简要总结
The goal of this clinical trial study is to investigate comparing Effects of Beetroot juice and Mediterranean diet on Liver Enzymes and Sonographic appearance in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD)
The main question[s] it aims to answer are:
- Beetroot juice has role in reduce Liver Enzymes
- Mediterranean diet has role in reduce Liver Enzymes
详细描述
Patients with NAFLD were identified and enrolled for this research at the PAR hospital in the Kurdistan Region of Iraq.
For 12 weeks, for the group members who were receiving the MeD, we recommended consuming Mediterranean foods like fish, poultry, sources of omega-3, vegetables and colored fruits, legumes and nuts, and low-fat goods while avoiding inflammatory foods like high-fat foods, processed meats, fast food, simple sugars, chips, and soft drinks.
At baseline, the participants' demographic and anthropometric information, including as gender, age, weight, height, smoking status, location of residence, and physical activity, were recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
盲法说明
Statical analyser
入排标准
- 年龄范围
- 19 Years 至 73 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients had to be between the ages of 19 and 73, and they had to have NAFLD as their main diagnosis.
- •For a NAFLD diagnosis, ultrasound proof of fatty liver (stage I or above) and an elevated level of liver enzymes were required.
排除标准
- •history of diseases like cardiovascular, liver, chronic hepatitis C, and kidney disease
- •supplement use within the previous six months; hormone therapy; use of drugs like amiodarone, methotrexate, and corticosteroids
- •cases of starvation or inadequate nutrition; pregnancy; metabolic disorders like Wilson disease and glycogen storage disease; a history of liver irradiation
结局指标
主要结局
Beetroot juice has role in reduce liver enzymes
时间窗: 12 weeks
Beetroot juice was given for 12 weeks and has role in reduce Serum Bilirubin, alkaline phosphatase (ALP), alanine transaminase (ALT), and liver enzyme was measured by blood sampling tests.
次要结局
- Mediterranean diet contributes to lower liver enzyme levels.(12 weeks)
研究者
Hawal Lateef Fateh
Dr Hawal Lateef Fateh
Sulaimany Polytechnic university