The effect of continuous positive airway pressure (CPAP) and non-invasive positive pressure ventilation (NIPPV) in acute cardiogenic pulmonary oedema (ACPO)

Completed

• Conditions: Cardiovascular diseases: Heart disease; Circulatory System; Heart disease

• Registration Number: ISRCTN07448447
• Lead Sponsor: Department of Health (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2003-04-25
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 1200

Inclusion Criteria

1. More than 16 years
2. Acute Cardiogenic Pulmonary Oedema (ACPO) principal clinical complaint
3. Confirmed diagnosis of ACPO

Exclusion Criteria

1. Patients needing immediate life-saving interventions
2. Inability to provide informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Added on the 12th June 2007:<br>1. NIV versus standard therapy: seven-day mortality<br>2. CPAP versus NIPPV: seven-day mortality or intubation

Secondary Outcome Measures

Name	Time	Method
Added on the 12th June 2007:<br>1. Physiology<br>2. Side-effects including Myocardial Infacrtion (MI)<br>3. Cost-effectiveness