EUCTR2011-004801-25-ES进行中（未招募）不适用
A PHASE I/II CLINICAL TRIAL OF THE BONE MARROW'S AUTOLOGOUS STEM CELLS IN PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS
Fundación Sanitaria para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana (FISABIO)0 个研究点开始时间: 2013年1月11日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Aged between 18 and 70 years.
- •- Diagnosis of definite or probable ALS according to the criteria
- •established by the World Federation of Neurology.
- •- Patient providing sufficient guarantees of adherence to protocol.
- •- Neurophysiological data confirming lower motor neuron involvement of lumbar level.
- •- No motor deficit in dorsiflexion of both feet (4 + or 5 points on the MRC)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 15
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 5
排除标准
- •- Diabetes Mellitus.
- •- Other diseases that may occur with polyneuropathy.
- •- A previous history of stroke.
- •- A previous pathology of peripheral nervous system that affects one or both lower limbs with or without clinically evident neurologic sequelae.
- •- Patients who are pregnant or breastfeeding active
- •- Patients physiologically capable of becoming pregnant, unless they are using reliable contraception (Annex III)
- •- Patients with heart, kidney, liver, systemic immune that may influence patient survival during the test.
- •- Positive serology for hepatitis B, hepatitis C or HIV.
- •- Clinical criteria and anesthesia sedation contraindicating either itself or extraction MO (Altered coagulation system or anticoagulated patient inability to withdraw anticoagulation, hemodynamic instability, altered skin puncture area, etc.)
- •- Included in other clinical trials in the last 6 months.
- •- Inability to understand informed consent.
研究者
相似试验
招募中
1 期
Mesenchymal stromal cell (MSC) therapy for COVID-19 pneumoniaCOVID-19 pneumoniaRespiratory - Other respiratory disorders / diseasesInfection - Studies of infection and infectious agentsACTRN12620000840987Royal Perth Hospital Cell & Tissue Therapies WA10
已完成
不适用
Phase one/ two clinical trial of boron neutro capture therapy for head and neck malignanciesHead and Neck cancersJPRN-UMIN000027543Kawasaki Medical School15
招募中
不适用
A phase II trial of the efficacy and safety of boring biopsy with rapid on-site evaluation for histological diagnosis of gastric mesenchymal tumorGastric mesenchymal tumorJPRN-UMIN000045414Osaka International Cancer Institute22
招募中
不适用
A Phase II trial to evaluate the efficacy of Bortezomib, Cytarabine, and Dexamethasone in patients with relapsed or refractory mantle cell lymphomaKCT0004010Seoul National University Hospital32
进行中（未招募）
1 期
A PARP inhibitor for inoperable, advanced endometrial cancer (PANDA).Inoperable, advanced, recurrent or metastatic endometrial cancerMedDRA version: 17.0Level: PTClassification code 10014733Term: Endometrial cancerSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2013-003469-32-GBniversity College London