NCT00226564
Completed
N/A
The Effect of mu Opioid Receptor Polymorphism on the Response to Alfentanil During Lithotripsy
ConditionsNephrolithiasis
DrugsAlfentanil
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Nephrolithiasis
- Sponsor
- Hadassah Medical Organization
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- Total alfentanil dose used during the procedure.
- Status
- Completed
- Last Updated
- 17 years ago
Overview
Brief Summary
The response to opioids varies greatly among individuals. Some of these variability is accounted for by genetic factors.
The present study was designed to evaluate the possibility that genetic polymorphism in the gene encoding for mu opioid receptor may explain variability in the response to alfentanil during lithotripsy.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \> 20
Exclusion Criteria
- •Regular use of opioid drugs
- •Known hypersensitivity to alfentanil
Outcomes
Primary Outcomes
Total alfentanil dose used during the procedure.
The extent of respiratory depression.
Study Sites (1)
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