A randomised trial to evaluate misoprostol for induction of labour following prelabour rupture of the amniotic membranes
Completed
- Conditions
- Induction of labourPregnancy and Childbirth
- Registration Number
- ISRCTN57007037
- Lead Sponsor
- iverpool Women's Hospital NHS Foundation Trust (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 1890
Inclusion Criteria
1. Decision to induce labour in the presence of PROM
2. >34 weeks gestation
3. Singleton, live fetus
4. Normal admission cardiotocograph (CTG)
Exclusion Criteria
1. Multiple pregnancy
2. Breech presentation
3. Previous Caesarean section
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Caesarean section (measure of safety)<br>2. Vaginal delivery within 24 hours of trial entry (measure of clinical effectiveness)
- Secondary Outcome Measures
Name Time Method 1. Labour<br>2. Delivery<br>3. Pueperium<br>4. Neonatal Morbidity<br>5. Satisfaction - Women's satisfaction, Caregiver's satisfaction<br>6. Womens' and midwives' views and experiences of participating in the PROMMIS Trial