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Clinical Trials/NCT05955963
NCT05955963
Active, not recruiting
Not Applicable

Bowel Sounds Analysis in Paediatric Inflammatory Bowel Disease: Relationship With wPCDAI

Centre Hospitalier Universitaire, Amiens1 site in 1 country49 target enrollmentJune 24, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bowel Sounds
Sponsor
Centre Hospitalier Universitaire, Amiens
Enrollment
49
Locations
1
Primary Endpoint
evaluation of wPCDAI
Status
Active, not recruiting
Last Updated
2 years ago

Overview

Brief Summary

The precise and noninvasive evaluation of disease activity among patients with Crohn's disease is not easy, especially for children. It deals with clinical, biological, histological and radiological parameters.

Bowel sounds (BS) when evaluated by a stethoscope are modified by several factors including surgery, infection, drugs or intestinal inflammation. These factors can interact on intestinal motricity. There is a direct relationship between gastrointestinal motility and characteristics of BW. The study of BS using a stethoscope is a simple method, although operator dependent and subjective,with a wide inter and intraindividual variability. Some studies among adults showed interest in the spectral analysis of BS to assess gastrointestinal motility. This more precise and reproducible method is not operator dependent.

To date, no such study has evaluated the correlation between disease activity and the spectral pattern of BS.

of this project is to assess the correlation between disease activity and the spectral pattern of BS in pediatric Crohn's disease.

Registry
clinicaltrials.gov
Start Date
June 24, 2021
End Date
June 4, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Crohn's Disease
  • Age between 4 and 17 years
  • Follow-up at CHU Amiens-Picardie

Exclusion Criteria

  • Other diseases than Crohn's or treatments affecting the gastrointestinal tract, recent (\< 3 months) surgery or refusal to participate (parents or children)

Outcomes

Primary Outcomes

evaluation of wPCDAI

Time Frame: one day

wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX

evaluation of frequency of bowel sounds

Time Frame: one day

correlation between wPCDAI and frequency of bowel sounds

Time Frame: one day

wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX

Study Sites (1)

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