Efficacy of epidural Platelet rich plasma v/s epidural steroid in low back pain

Phase 3

Not yet recruiting

Conditions: Unspecified soft tissue disorder related to use, overuse and pressure,

Registration Number: CTRI/2023/09/057982

Lead Sponsor: Adarsh Jayasoorya t

Brief Summary: Lower back pain (LBP) is a prevalent medical condition that frequently results in work related disability and is one of the leading causes of missed workdays. According to Andersson, the annual global incidence of LBP in adults is 15%, while the point prevalence is 30%(1). Exercise has the potential to make this back pain worse, which ultimately results in avoidance of activity and impairment. It is one of the most prevalent issues seen in orthopaedic practise and one of the most major costs placed on the healthcare system. 70% to 85% of people are predicted to suffer with LBP at some point in their lives. Ninety percent of these people will experience multiple episodes(2-4), and an intervertebral disc prolapse accounts for a significant portion of that.Medications and lifestyle adjustments may be used as the first line of treatment, but if the symptoms do not improve, minimally invasive procedures such as epidural steroid injection and epidural platelet rich plasma injection may be used to relieve the pain and lessen disability. We therefore aim to conduct a study to analyze the patientâ€™s functional status and satisfaction after epidural platelet rich plasma infiltration. Visual analogue scale and Oswestry disability index are used to measure the outcome.

The follow up scores are taken post three weeks and three months of the treatment

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 64

Inclusion Criteria

All Skeletally matured patients Diagnosed cases of lumbar intervertebral disc prolapse Having complaints of backpain with radiculopathy for more than 4 weeks with a positive straight leg raising test.

Exclusion Criteria

Patient with infection, traumatic spine injuries, spinal tumors, spinal deformities and congenital spinal anomalies, bleeding disorders.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Epidural PRP infiltration is expected to have a better outcome as compared to epidural steroid infiltration for low back pain	Patients will be evaluated after 1 hour of procedure & will be followed up at 3 weeks & 3 months

Secondary Outcome Measures

Name	Time	Method

Trial Locations

Locations (1): Jawaharlal Nehru Medical College
🇮🇳
Wardha, MAHARASHTRA, India
Jawaharlal Nehru Medical College
🇮🇳Wardha, MAHARASHTRA, India
Adarsh Jayasoorya T
Principal investigator
9645341631
adarshjayasurya@gmail.com