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Retrospective Study in the Use of the Alfapump and the Treatment of Malignant Ascites

Completed
Conditions
Malignant Ascites
Registration Number
NCT03200106
Lead Sponsor
Sequana Medical N.V.
Brief Summary

Treatment of malignant ascites with the alfapump offers a new treatment option for this patient group. So far, there is no systematic analysis of patients with this indication available in the literature.

This retrospective analysis offers the possibility to assemble already existing data within a reasonably short time frame. Based on this analysis, a prospective analysis can be designed.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
17
Inclusion Criteria
  • Patients with malignant ascites
  • Patients with alfapump implanted for malignant ascites
  • Patients 18 years or older at the time of death
Exclusion Criteria
  • Patient is alive at the time of inclusion assessment

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in frequency of LVP after implantation of the alfapump3-6 months post implant

The primary objective of the study is to evaluate the performance of the alfapump in reducing the need for large volume paracentesis (LVP) defined as paracentesis of five or more litres of ascites and not by pump paracentesis.

Secondary Outcome Measures
NameTimeMethod
The safety and tolerability of alfapump in patients with malignant ascites3-6 months post implant

Device, procedure and therapy related AEs and SAEs

Trial Locations

Locations (3)

Hammersmith Hospital

🇬🇧

London, United Kingdom

Inselspital

🇨🇭

Bern, Switzerland

Universitätsklinikum Leipzig

🇩🇪

Leipzig, Germany

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