Cross-sectional Study on the Incidence,Factors,and Importance of Brown Adipose Tissue in Adult Chinese
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
研究概览
简要总结
Previous studies have shown that active brown adipose tissue (BAT) is present in adults and may play important roles in material and energy metabolism. However, most of these studies were tumor-based populations and retrospective study. Due to the large amount in our cohort, the investigators are able to promote a cross-sectional study of the incidence and factors of BAT in adult chinese. In addition, the investigators can analyse the metabolic profiles in healthy adults with active BAT.
详细描述
The investigators will perform a cross sectional analysis on the chinese adults who use 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) to scan the whole body at Huashan Hospital from 2009 to 2013. BAT activity will be measured by PET/CT. Not only demographic data on sex, age, medication and medical history,but also data on body composition and physical examination will be collected for all subjects. Imaging date,outdoor temperature and fasting blood samples will be collected as well. In addition, the investigators will analyse the metabolic profiles in healthy adults with active BAT and their negative controls,such as lipid profiles,fasting glucose and insulin sensitivity, adipokines and other biochemical markers.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects with detectable brown adipose tissue
- •Negative controls,consisting of one subject who underwent PET/CT scans at the same day but without detectable BAT
排除标准
- •Younger than 18 years
- •Pregnant women
- •With implantable medical electronic instrument