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Clinical Trials/NCT07318220
NCT07318220
Recruiting
Not Applicable

Optimizing Cancer Support Services Usage in Patients With Head and Neck Cancer During the Prehabilitation Period

University of Miami1 site in 1 country60 target enrollmentStarted: April 30, 2026Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Enrollment
60
Locations
1
Primary Endpoint
Aim 2: Feasibility of Participant Engagement in Prehabilitation Prescription Program

Overview

Brief Summary

The purpose of this research is to help researchers understand the barriers, supports, and preferences for prehabilitation. Prehabilitation in this study means head and neck cancer patients will receive nutritional counseling sessions and attend exercise programs before and during radiotherapy/chemoradiotherapy treatment.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Prevention
Masking
None

Eligibility Criteria

Ages
18 Years to 80 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Aim 2 Inclusion Criteria: Implement prehabilitation prescription protocol and evaluate the feasibility and acceptability of the prehabilitation prescription protocol in a sample of HNC patients.
  • Age 18 to 80 years old
  • Patients with a diagnosis of non-metastatic squamous cell carcinoma originating in the head and neck (oral cavity, oropharynx, hypopharynx, larynx, and nasopharynx).
  • Patients with a plan for curative radiation therapy (RT) / chemoradiation therapy (CRT) at SCCC\* - \*Patients who underwent surgery for the HNC are still eligible.
  • Clearance for exercise by the medical team.
  • Patients who do not have their first treatment scheduled within 3 weeks at the time of recruitment.
  • An English or Spanish speaker.

Exclusion Criteria

  • A patient with a metastatic cancer.
  • A patient who cannot complete the baseline assessment and/or start prehabilitation by the initiation of RT/CRT.
  • Any contraindication for diet change or exercising as determined by a physician.
  • Engaging in \>150 minutes of moderate to vigorous physical activity on average per week for the prior month.
  • A patient who is not an English or Spanish speaker.
  • History of dementia or major psychiatric disease which would interfere with study.
  • History of recent (≤1 yr) stroke, myocardial infarction, or congestive heart failure
  • Eastern Cooperative Oncology Group (ECOG) equal to or higher than 2.

Outcomes

Primary Outcomes

Aim 2: Feasibility of Participant Engagement in Prehabilitation Prescription Program

Time Frame: Up to 18 Weeks

Feasibility will be measured as the percentage of participants that agree to participate in the prehabilitation prescription protocol. Criterion for success: At least (≥) 50% of all eligible participants agree to participate in the prehabilitation prescription protocol.

Aim 2: Feasibility of Participant Attendance to Scheduled Visits of the Prehabilitation Prescription Protocol

Time Frame: Up to 18 Weeks

Feasibility will be measured as the percentage of participants attending scheduled visits of the prehabilitation prescription protocol. Criterion for success: At least (≥) 70% of participants attend all scheduled visits.

Aim 2: Acceptability of Participants That Feel Satisfied with the Prehabilitation Prescription Protocol

Time Frame: Up to 18 Weeks

Acceptability will be measured as the percentage of participants that report satisfaction with the prehabilitation prescription protocol. Criterion for success: At least (≥) 80% of participants complete the prehabilitation prescription protocol.

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Akina Natori

Research Assistant Professor

University of Miami

Study Sites (1)

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