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临床试验/NCT03010930
NCT03010930已完成不适用

Does Repeated Dietary Exposure to Umami Taste Affect Umami Perception, Hedonics, or Satiety? A Randomized Controlled Study

Cornell University0 个研究点目标入组 64 人开始时间: 2016年10月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
64
主要终点
Change in umami taste intensity perception

研究概览

简要总结

The purpose of this study is to determine how repeated dietary exposure to umami taste affects umami taste perception, hedonics, food preferences, and satiety. Healthy adult subjects will consume a low glutamate vegetable broth daily for one month, where the experimental group's broth is supplemented with the umami-rich stimuli of monosodium glutamate (MSG) and the control group's low glutamate broth is matched for sodium (NaCl).

The investigators hypothesize that repeated dietary exposure to umami taste will:

  1. diminish umami suprathreshold intensity perception and hinder the ability to discriminate varying MSG concentrations
  2. decrease liking of umami-rich foods and shift preferences upwards towards more intense umami stimuli
  3. decrease satiation and decrease the satiating effect of a test meal

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Have normal sense of taste and smell (self-report)
  • Likes soups or broths (self-report)
  • Able to report to study site daily (self-report)

排除标准

  • Restrained eater (score > 12 on restrained eating subscale from Three Factor Eating Questionnaire)
  • BMI < 18 or > 25 kg/m2 (self-report)
  • Vegan (self-report)
  • Hypertensive or on low-sodium diet (self-report)
  • Allergic or sensitive to MSG (self-report)

结局指标

主要结局

Change in umami taste intensity perception

时间窗: 1 month (at baseline and post intervention)

Subjects rate the umami intensity of aqueous solutions and foods on the general Labeled Magnitude Scale before and after a month-long dietary supplementation to determine how perception changes with repeated exposure to umami taste

Change in umami taste discrimination

时间窗: 1 month (at baseline and post intervention)

Subjects rank solutions of varying umami intensity before and after a month-long dietary supplementation to determine how perception changes with repeated exposure to umami taste

次要结局

  • Change in umami liking and preference(1 month (at baseline and post intervention))
  • Change in satiation(1 month (at baseline and post intervention))
  • Change in liking and wanting of high protein foods(1 month (at baseline and post intervention))
  • Change in satiety(1 month (at baseline and post intervention))

研究者

申办方类型
Other
责任方
Sponsor

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