NCT06437717已完成不适用
Role of Nanoemulsified Sesame Oil in Post-operative Care After Endoscopic Sinus Surgery
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Sinonasal Outcome Test 22 (SNOT-22)
研究概览
简要总结
The goal of our thesis is to design, develop and characterize a novel thermodynamically stable NE by spontaneous method intended for topical use. Subsequently, appraisal of nanoemulsified sesame oil formulation has been performed on the post-operative symptoms in CRS patients who have undergone ESS (endoscopic sinus surgery) combined with different types of nasal irrigation which may affect formulation efficacy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient age between 18 and 60 years old.
- •chronic rhinosinusitis patients who have undergone endoscopic sinus surgery.
排除标准
- •Patients with history of allergy for sesame seed derivatives.
- •Patients with chronic diseases which affecting the process of healing (uncontrolled DM, renal failure and hepatic failure).
- •Patients with nasal granulomas.
- •Patients with invasive fungal rhinosinusitis.
- •Patients with history of radio and/or chemotherapy exposure.
- •Patients with systemic diseases affecting integrity of nasal mucosa (e.g. CF, scleroderma, Sjogren syndrome …).
结局指标
主要结局
Sinonasal Outcome Test 22 (SNOT-22)
时间窗: weekly for three months
Lund-Kennedy endoscopic grading system
时间窗: once monthly for three months
次要结局
未报告次要终点
研究者
Noha A.Elkholy
Lecturer
Mansoura University
研究点 (2)
Loading locations...
相似试验
招募中
2 期
Sesame oil wafers for alleviation of dry mouth.Post-treatment xerostomia in head and neck cancer patients.Sesame oil, Saliva Substitute, Head &Neck cancer, Oral mucositis, Dry mouth, and XerostomiaTCTR20240326002Research unit, Faculty of Dentistry, Prince of Songkla University34
已完成
不适用
Evaluation of the effect of topical Sesame Oil in the Prevention of Chemotherapy-Induced Phlebitis in 17 Shahrivar Hospitalphlebitis.Vascular complications following infusion, transfusion and therapeutic injectionIRCT2015101924594N1Guilan University of Medical Sciences60
已完成
不适用
Effect of external use of Sesame oil in the prevention of chemotherapy-induced phlebitisphlebitis.Vascular complications following infusion, transfusion and therapeutic injectionIRCT138903082846N7Researcher60
Approved For Marketing
不适用
Compassionate Use of Omegaven® for the Treatment of Intestinal Failure Associated Liver Disease in ChildrenTotal Parenteral Nutrition-Induced CholestasisNCT02328768University of Nebraska
已完成
不适用
Efficacy and safety of a new fish oil based lipid emulsion (SMOFlipid) compared with olive oil based lipid emulsion (Clinoleic) in pre term (<30 weeks) neonates – a randomised controlled trialeonatal nutrtionNeonatal nutrtionDiet and Nutrition - Other diet and nutrition disordersACTRN12609001017213KING EDWARD MEMORIAL HOSPITAL FOR WOME30