TCTR20180619003Enrolling By Invitation未知
Impact of CYP3A5 polymorphisms on intra-patient variability of tacrolimus pharmacokinetics in kidney transplant recipients
适应症
试验速览
- 阶段
- 未知
- 状态
- Enrolling By Invitation
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 0 N/A (No limit)（—）
- 性别
- All
入选标准
- •1) age over 18 years old
- •2) immunosuppressive therapy based on twice-daily tacrolimus (Prograf®)
- •3) graft survival for at least 6 months after transplantation.
排除标准
- •1) were multiorgan transplanted
- •2) died or graft lost for any reason before study begins
- •3) had history of active liver disease during 6 and 12 months after transplantation such as cirrhosis, viral hepatitis or hepatocellular carcinoma
- •4) received any medications that can interfere tacrolimus pharmacokinetics, with the exception of PPI drug group
- •5) had history of medication noncompliance in patient record
- •6) data did not complete.
研究者
相似试验
已完成
不适用
Healthy Volunteer CYP3A5 Genotype studyCTRI/2018/10/016104ithya Gogtay400
招募中
2 期
Effects of genetic polymorphism of CYP3A5 and UGT1A9 in brain-death donor and liver transplant recipients on pharmacokinetic profiles of tacrolimus and mycophenolate at steady state post-transplantatioThai liver transplant patients (cadaveric liver transplant)Thai liver transplant patients (cadaveric liver transplant),CYP3A5 and UGT1A9 polymorphisms,PharmacokineticsTCTR20190707002Rachadapisek Sompote Fund.20
进行中（未招募）
1 期
The influence of CYP3A5 and ABCB1 genotype on the pharmacokinetics of twice daily Tacrolimus and Advagraf - Pharmacogenetics of twice daily Tacrolimus and AdvagrafRenal transplantation.MedDRA version: 14.1 Level: LLT Classification code 10023438 Term: Kidney transplant System Organ Class: 100000004865EUCTR2009-013461-25-GBSt. George's, University of London330
已完成
不适用
Genetic study in renal transplant patientsCTRI/2018/04/013495Seth GS Medical College and KEM Hospital150
Unknown
4 期
Influence of CYP3A5 Polymorphism on Liver Function Abnormality and the Trough Level Change After ConversionLiver DysfunctionNCT02882113Seoul National University Hospital60