The role of selective neck dissection in patients with early oral squamous cell carcinoma (1-3cm primary size) and no clinical evidence of lymph node metastases in the neck (N0)

Queen Mary University of London0 个研究点目标入组 596 人开始时间: 2010年4月23日最近更新: 2022年11月7日

适应症

试验速览

2019 Results article in https://pubmed.ncbi.nlm.nih.gov/31611612/ results (added 12/06/2020)

•1. Patients with oral squamous cell carcinoma (OSCC) measuring 1 to 3 cm at the primary site (ICD9 codes: 141, 143, 144, 145, 146, 149)
•2. No clinical or preoperative imaging evidence of nodal involvement in the neck (N0 neck)
•3. Surgery is the primary mode of treatment
•4. Age 16 years and over, either sex
•5. Capable of giving written informed consent

•1. Cancer of the lip (ICD9 code 140)
•2. Previous head and neck tumour
•3. Other synchronous tumour
•4. Technical, medical or anaesthetic difficulties which preclude patients being entered into one of the trial arms
•5. Where the surgeon assesses that the patient needs reconstruction that necessitates opening the neck
•6. Those patients whom the multi-disciplinary team meeting considered to be medically, socially or psychiatrically unfit for surgery as first line treatment
•7. Those patients where the patient expresses a preference for non-surgical treatment

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