Efficacy of Thatbunjob remedy in symptom relief of patient with irritable bowel syndrome: a pilot study
Phase 2
- Conditions
- Irritable bowel syndrome characterized by chronically recurring abdominal pain or discomfort and altered bowel habits,is one of the most common syndromes seen by gastroenterologists and primary careThatbunob,Irreversible bowel syndrome
- Registration Number
- TCTR20191223004
- Lead Sponsor
- Faculty of medicine, Thammasat University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Abdominal pain at least 1 day per week for the past 3 months associated with two or more of the following:
-Improvement with defecation
-Onset associated with a change in frequency of stool
Exclusion Criteria
1.Indication or contraindication to antiplatelet or anticoagulant therapy.
2.A clinically significant bleeding diathesis.
3. Positive pregnancy test, breast feeding
4. Risk of colon cancer include
- Weight loss > 10% in the previous 3 months.
- Positive of stool occult blood
- Anemia
-Hepatomegaly, gastric tumor, Lymphadenopathy, jaundice
- Family history of colon cancer
5) Inconvenience to go to Thammasat hospital
6) ALT is higher than 3 times of upper limit of normal
7) eGFR is lower than 60 mL/min
8) Allergic to herbal drug
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain, Bloating and stool frequency of IBS IBS symtom will be recorded by the participant daily until Day 1 to Day 21 Pain score, Bloating score and stool frequency score
- Secondary Outcome Measures
Name Time Method Quality of life The begining of the study and Day 21 EQ5D5L of EuroQol Research Foundation ,Side effect of Thatbunjob 1 day and 7 days after stopping drug study Blood test for AST, ALT, creatinine, eGFR, CBC