The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Interstitial Pulmonary Fibrosis ARDS
- Sponsor
- Yonsei University
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- arterial blood oxygen partial pressure (PaO2)
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
ECMO(Extracorporeal membrane oxygenation) is being essential for cardiopulmonary failure patients. There are two types of ECMO, which is veno-veno (V-V) that can be used in respiratory failure patients and veno-arterial (V-A) that can be used in cardiac failure patients. V-A ECMO can also be used during lung transplantation, substitution of cardiopulmonary bypass, which can show sufficient performance during operation and better postoperative outcome. However, regarding V-A ECMO circulating from femoral vein to femoral artery, there is a pro blem of differential hypoxia which might influence coronary artery and head vessels. In this prospective study, the investigators are planning to put another ECMO catheter into internal jugular vein which takes a role of left to right shunt, to mitigate the hypoxia of coronary artery.
Investigators
Eligibility Criteria
Inclusion Criteria
- •scheduled for double lung transplantation
Exclusion Criteria
- •patients who have history of coronary artery occlusive disease
- •patients with arrhythmia
Outcomes
Primary Outcomes
arterial blood oxygen partial pressure (PaO2)
Time Frame: 5 min after jugular catheter flow 1,500ml/min
Secondary Outcomes
- venous blood oxygen partial pressure (PvO2)(5 min after jugular catheter flow 1,500ml/min)