跳至主要内容
临床试验/NCT02859194
NCT02859194已完成不适用

The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients

Yonsei University2 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2016年5月31日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
10
试验地点
2
主要终点
arterial blood oxygen partial pressure (PaO2)

研究概览

简要总结

ECMO(Extracorporeal membrane oxygenation) is being essential for cardiopulmonary failure patients. There are two types of ECMO, which is veno-veno (V-V) that can be used in respiratory failure patients and veno-arterial (V-A) that can be used in cardiac failure patients. V-A ECMO can also be used during lung transplantation, substitution of cardiopulmonary bypass, which can show sufficient performance during operation and better postoperative outcome. However, regarding V-A ECMO circulating from femoral vein to femoral artery, there is a pro blem of differential hypoxia which might influence coronary artery and head vessels. In this prospective study, the investigators are planning to put another ECMO catheter into internal jugular vein which takes a role of left to right shunt, to mitigate the hypoxia of coronary artery.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • scheduled for double lung transplantation

排除标准

  • patients who have history of coronary artery occlusive disease
  • patients with arrhythmia

研究组 & 干预措施

Veno-veno-arterial ECMO group

Experimental

干预措施: Veno-veno-arterial ECMO (Procedure)

结局指标

主要结局

arterial blood oxygen partial pressure (PaO2)

时间窗: 5 min after jugular catheter flow 1,500ml/min

次要结局

  • venous blood oxygen partial pressure (PvO2)(5 min after jugular catheter flow 1,500ml/min)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验