Skip to main content
Clinical Trials/NCT02859194
NCT02859194
Completed
Not Applicable

The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients

Yonsei University1 site in 1 country10 target enrollmentMay 31, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Interstitial Pulmonary Fibrosis ARDS
Sponsor
Yonsei University
Enrollment
10
Locations
1
Primary Endpoint
arterial blood oxygen partial pressure (PaO2)
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

ECMO(Extracorporeal membrane oxygenation) is being essential for cardiopulmonary failure patients. There are two types of ECMO, which is veno-veno (V-V) that can be used in respiratory failure patients and veno-arterial (V-A) that can be used in cardiac failure patients. V-A ECMO can also be used during lung transplantation, substitution of cardiopulmonary bypass, which can show sufficient performance during operation and better postoperative outcome. However, regarding V-A ECMO circulating from femoral vein to femoral artery, there is a pro blem of differential hypoxia which might influence coronary artery and head vessels. In this prospective study, the investigators are planning to put another ECMO catheter into internal jugular vein which takes a role of left to right shunt, to mitigate the hypoxia of coronary artery.

Registry
clinicaltrials.gov
Start Date
May 31, 2016
End Date
October 14, 2016
Last Updated
7 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • scheduled for double lung transplantation

Exclusion Criteria

  • patients who have history of coronary artery occlusive disease
  • patients with arrhythmia

Outcomes

Primary Outcomes

arterial blood oxygen partial pressure (PaO2)

Time Frame: 5 min after jugular catheter flow 1,500ml/min

Secondary Outcomes

  • venous blood oxygen partial pressure (PvO2)(5 min after jugular catheter flow 1,500ml/min)

Study Sites (1)

Loading locations...

Similar Trials