ong-term beta-blocker therapy after acute myocardial infarctio

Not Applicable

Recruiting

Conditions: Diseases of the circulatory system

Registration Number: KCT0005903

Lead Sponsor: Samsung Medical Center

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 2500

Inclusion Criteria

Male or female, 19 years of age or older
- Diagnosed with acute myocardial infarction regardless of the time of myocardial infarction and has been treated for beta-blockers for more than a year
- Signed Informed Consent Form

Exclusion Criteria

- less than 40% left ventricular blood pressure or has never had a cardiac ultrasonography in cardiac ultrasonography since an acute myocardial infarction.
- Medication Therapy of heart failure
-contraindications to beta blockers
i)prior history of symptomatic asthma or chronic obstructive pulmonary disease
ii)Patients with a history of 2-degree, 3-degree, or artificial pacemaker
iii)If the investigator decision to used not beta-blockers
-If the life anticipation 1year under, or Poor protocol compliance
-History of atrial fibrillation
-pregnant and breast-feeding

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major adverse cardiovascular events [MACE], a composite of all-cause death, myocardial infarction [MI], hospitalization for heart failure

Secondary Outcome Measures

Name	Time	Method
2 Years of all-cause Death After Random Allocation;2 Years of Cardiac death After Random Allocation;2 Years of myocardial infarction After Random Allocation;2 Years of All-cause hospitalizations After Random Allocation;2 Years of heart failure hospitalizations After Random Allocation;2 Years of Acute coronary syndrome hospitalizations After Random Allocation;2 Years of death or myocardial infarction After Random Allocation;2 Years of Cardiac death or myocardial infarction After Random Allocation;2 Years of myocardial infarction or heart failure hospitalizations After Random Allocation;2 Years of all re-CAG After Random Allocation;2 Years of myocardial infarction or all re-CAG After Random Allocation;2 Years of Cardiac death, myocardial infarction or all re-CAG After Random Allocation;2 Years of left ventricular implementation rate After Random Allocation;NT-proBNP at 2years;total medical expenses;quality of life scale;side effects of beta blocker