Comparison of the Effectiveness of Physical Therapy With Ultrasound-Guided Radiofrequency Ablation of the Genicular Nerve in Patients With Chronic Knee Osteoarthritis
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 68
- 试验地点
- 2
- 主要终点
- Visual Analog Scale (VAS)
研究概览
简要总结
The aim of this study is to compare the effects of conventional physiotherapy methods with ultrasound-guided radiofrequency ablation of the genicular nerve on pain and functional status in patients with stage 2-3 chronic knee osteoarthritis.
详细描述
Patients diagnosed with Chronic Knee Osteoarthritis according to the American College of Rheumatology criteria, and with radiological osteoarthritis at Kellgren-Lawrence grades 2 and 3, within the age range of 45-70, and meeting the study criteria will be included in the study. After providing information about the procedures to be performed and potential risks to the patients, if they give their written informed consent, treatment methods will be applied to the patients. Eligible patients will be divided into two groups. In one group, Radiofrequency Ablation of the Genicular Nerve under Ultrasound Guidance will be performed, while the other group will receive physical therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 45 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •To be aged between 45 and 70 years old
- •Patients diagnosed with chronic knee osteoarthritis using the American College of Rheumatology criteria and having radiological osteoarthritis of Kellgren-Lawrence grade 2 and 3
- •Cognitive functions being intact
- •Being willing to participate in the study and signing the consent forms
排除标准
- •Having received physical therapy for chronic knee osteoarthritis in the last 6 months
- •Having received glucocorticoid or hyaluronic acid injections in the last 6 months
- •Having taken oral glucosamine
- •Undergoing knee surgery
- •Having current neurological or mental disorders
- •History of pacemaker usage
- •Presence of local infections or sepsis
- •Progressive neurological deficit
- •Presence of oncological diseases
- •Hemorrhagic diathesis or anticoagulation
- •Uncontrolled diabetes or other serious internal comorbidities
- •Allergy to medications or materials used
- •Pregnancy
- •Lack of cooperation
- •Not willing to participate in the study.
结局指标
主要结局
Visual Analog Scale (VAS)
时间窗: Before treatment (initial), after 2 weeks and 12 weeks changes
Scale. The Visual Analog Scale (VAS) is evaluated on a scale ranging from "no pain" to "worst possible pain." The value of 0 (zero) indicates "no pain," while the value of 10 (ten) indicates "the most severe pain imaginable."
次要结局
- The 6-minute walk test (6MWT)(Before treatment (initial), after 2 weeks and 12 weeks changes)
- EuroQol scale (EQ-5D-3L)(Before treatment (initial), after 2 weeks and 12 weeks changes)
- The Western Ontario and McMaster Universities Arthritis Index (WOMAC)(Before treatment (initial), after 2 weeks and 12 weeks changes)
研究者
Merve Çakır
medical doctor
Ankara City Hospital Bilkent