Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances
试验速览
- 阶段
- 不适用
- 入组人数
- 80
研究概览
简要总结
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not demonstrated. Our hypothesis is that patients suffering from a more severe sleep apnea will demonstrate a greater degree of cognitive dysfunction.
详细描述
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of sleep disturbances and the degree of cognitive dysfunction was not demonstrated.We intend to study 80 patients with various degrees of obstructive sleep apnea. All patients will undergo executive cognitive tests as well as tests to assess for levels of depression, anxiety and attention.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Apnea hypopnea index>5
- •Age 20 - 70 years
排除标准
- •Pregnant women
- •Known chronic cardiovascular or pulmonary disease
- •Patients s/p CVA or brain damage
- •Known depression or other psychiatric disorder
- •Patients with severe cognitive dysfunction (MMSE<25)
- •Patients receiving stimulants, antipsychotic or anti-depression medications