Obstructive Sleep Apnea Syndrome and Attention Executive Function Disturbances
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obstructive Sleep Apnea
- Sponsor
- Assaf-Harofeh Medical Center
- Enrollment
- 80
- Last Updated
- 17 years ago
Overview
Brief Summary
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of obstructive sleep apnea and the degree of cognitive dysfunction was not demonstrated. Our hypothesis is that patients suffering from a more severe sleep apnea will demonstrate a greater degree of cognitive dysfunction.
Detailed Description
Studies demonstrate that sleep disturbances are associated with cognitive dysfunction and attention deficit. However the correlation between the severity of sleep disturbances and the degree of cognitive dysfunction was not demonstrated.We intend to study 80 patients with various degrees of obstructive sleep apnea. All patients will undergo executive cognitive tests as well as tests to assess for levels of depression, anxiety and attention.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Apnea hypopnea index\>5
- •Age 20 - 70 years
Exclusion Criteria
- •Pregnant women
- •Known chronic cardiovascular or pulmonary disease
- •Patients s/p CVA or brain damage
- •Known depression or other psychiatric disorder
- •Patients with severe cognitive dysfunction (MMSE\<25)
- •Patients receiving stimulants, antipsychotic or anti-depression medications
Outcomes
Primary Outcomes
Not specified