Effect of PRP-Fibrin glue and Repairing gel in treatment of second-degree burn wounds

Phase 2

Conditions: Burn of second degree.
Burn of second degree, body region unspecified
T30.2

Registration Number: IRCT20191228045924N6

Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 40

Inclusion Criteria

Confirmation of second-degree burns
Having a body mass index of 18-35
No smoking, alcohol and drug addiction
Not taking drugs that may interfere with wound healing, such as corticosteroids, immunosuppressive agents, and cytotoxic agents
Not having concurrent diseases that may cause problems in wound healing, such as cancers, vasculitis, kidney, liver, and heart failures
Informed consent of patients

Exclusion Criteria

The presence of a wound with an active infection requiring intravenous antibiotics or gangrene requiring amputation
Failure to refer the patient to the mentioned center for follow-up and dressing change on more than two occasions

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Visual Analog Scale changes for pain assessment. Timepoint: Every 48 hours for 8 weeks. Method of measurement: Pain will be evaluated by the visual analog scale system (VAS). The score is determined by measuring the distance (mm) between the no-pain anchor and the point that the patient marks, providing a range of scores from 0 - 10. A higher score indicates greater pain intensity.;The duration of recovery is the number of days it will take for the wound to heal. Timepoint: The interval from the beginning of the study (0 days) to wound healing. Method of measurement: Counting days.;Change from Baseline Wound Size (length and width) will be assessed in digital images taken of the wound. Timepoint: At the beginning of the study (0 days) and at the end of the eighth week of the intervention (8 weeks). Method of measurement: digital images and ruler.

Secondary Outcome Measures