A clinical trial to study the efficacy of the drug misoprostol administered rectally in reducing excessive bleeding after normal delivery
- Conditions
- Women with singleton pregnancy undergoing normal vaginal delivery
- Registration Number
- CTRI/2014/08/004910
- Lead Sponsor
- DrSMCSIMedical college
- Brief Summary
This study is a randomized double blind placebo controlled trial to find the efficacy of 400mcg of rectal Misoprostol given after the delivery of the baby (in addition to standard dose of 10 units Oxytocin IM injection), in reducing postpartum haemorrhage in 320 patients undergoing vaginal delivery in Dr SM CSI Medical College Hospital for a period of one year. The primary outcome measures will be fall in haemoglobin and PCV levels after 24 hours of delivery. The secondary outcome will be duration of third stage of labour
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Female
- Target Recruitment
- 320
women with singleton pregnancy cephalic presentation >28 weeks of gestational age Hb>10gms.
patients undergoing cesarean section and instrumental delivery malpresentation multiple pregnancy past history of post partum haemorrhage coagulopathies heart disease/renal disease placenta previa/abruptio placenta.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fall in haemoglobin and PCV levels 24 hours
- Secondary Outcome Measures
Name Time Method Duration of third stage of labour
Trial Locations
- Locations (1)
Labour Room
🇮🇳Thiruvananthapuram, KERALA, India
Labour Room🇮🇳Thiruvananthapuram, KERALA, IndiaDr Ranjula Golda Lysander RPrincipal investigator9443253672ranjulasandeep@gmail.com