MedPath

Effectiveness of lipofilling in patients with impaired speech and/or swallowing function after treatment for head and neck cancer

Phase 2
Recruiting
Conditions
Functionele aandoeningen (slik en spraakproblemen)
Swallowing- and speech impairment
Registration Number
NL-OMON44636
Lead Sponsor
Antoni van Leeuwenhoek Ziekenhuis
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
19
Inclusion Criteria

Patients with chronic, refractory speech and/or swallowing problems after treatment for head and neck cancer
According to the rehabilitative care team, there is no other option except lipofilling

Exclusion Criteria

-

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Speech outcomes:<br /><br>- Objective outcomes: Intelligibility, diadochokinesis, voice quality and vowel<br /><br>space.<br /><br>- Subjective outcomes: Speech Handicap Index<br /><br><br /><br>Swallowing outcomes:<br /><br>- Objective outcomes: Penetration-aspiration scale, residue after swallowing,<br /><br>Functional Oral Intake Scale en weight change.<br /><br>- Subjective outcomes: EORTC QLQ-C30 en H&N35 en SWAL-QOL</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Effect on tongue base volume, feasibility and patients' satisfaction. </p><br>
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