A clinical research regarding an inhalation therapy of the low concentration carbon monoxide (CO) in patients with chronic obstructive pulmonary disease (COPD) and secondary pulmonary artery hypertension (sPAH)
Not Applicable
- Conditions
- COPD and sPAH
- Registration Number
- JPRN-UMIN000002080
- Lead Sponsor
- Tohoku University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1.Patients exposed to high level of ambient CO whose arterial Hb-CO (aHb-CO) concentration was more than 3.0% 2.Current smoker within 4 weeks 3.Patients with cardiac, hepatic, or hematologic diseases 4.Patients with abnormalities of blood coagulation or fibrinolysis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean pulmonary artery pressure
- Secondary Outcome Measures
Name Time Method Dyspnea scale (Hugh-Jones scale), distance in 6 minutes walking test, lung function, lipid peroxide, and peripheral blood IL-10 level