se of pneumatic needle-free hyaluronic acid injection technology for correction of atrophic facial acne scars in adult patients: a randomized placebo-controlled split-face comparative study.
- Conditions
- atrophic facial acne scarsatrophic scarD001284
- Registration Number
- JPRN-jRCTs052190078
- Lead Sponsor
- Yuki Yamamoto
- Brief Summary
The findings of this study suggest that PA-HA treatment is effective against all severity rolling type atrophic facial acne scars in Japanese subjects and has minimal AEs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Male or female 25-65 years old. Presence of more than 4 distensible facial moderate to severe atrophic acne scars.
Patient with having severe underlying disease, pregnancy or lactation, Porphyria, cardiac conduction disturbance, allergic conditioned, local anesthesia allergies and hyaluronic acid produced allergies previously, vascular or bleeding disorders, treated with anticoagulant therapy, autoimmune disease, treated with immunosuppressive therapy, keloid scar formation, hypertrophic scar formation, malignant skin tumor, pigment anomaly, inflammatory disease that a symptom may aggravate in irritation by a treatment, medical history of herpesvirus infection. Invasive aesthetic treatments or facial surgery within 6 months prior to the study enrollment.
Physical or chemical aesthetic treatments within 3 month prior to the study enrollment. Clinically significant acne in the proposed treatment areas defined as more than 3 active inflammatory acne lesions in the treatment areas.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall judgment of therapeutic efficacy
- Secondary Outcome Measures
Name Time Method time-to-treatment-failure, adverse events