Pulse wave velocity and intima-media thickness as an indication of cardiovascular degeneration in patients after chemotherapy in childhood and adolescence.
- Conditions
- C40C41C47C64C65C71C83Malignant neoplasm of brainC74C81
- Registration Number
- DRKS00005642
- Lead Sponsor
- niversistätsklinikum Halle
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 106
Inclusion Criteria
All patients in the pediatric cardiology department of the MLU who are cared for in one year between the ages of 1-31 years with a condition after cardiotoxic therapy in the context of an oncological disease in children and adolescents. The primary chemotherapy of these patients is more than a year and the last chemotherapy is more than two months ago.
Exclusion Criteria
Patients whose primary chemotherapy is less than one year and whose last chemotherapy is less than two months old or who do not meet the inclusion criteria.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pulse wave speed: When lying down, after a rest period of five minutes, the standardized system of the Mobil-O-Graphen® PWA (I.E.M., Stolberg, Germany) takes place on the left upper arm.<br><br>Intima-media thickness:<br>Intima-media thickness at the common carotid artery (ACC) with a linear sound head (IPx-7 L12-5 50, 12-5 MHz, Philipps) and the preset thyroid (24-42Hz) according to the leading-edge method trained doctor or doctoral student.
- Secondary Outcome Measures
Name Time Method