Perioperative Cardiac Arrest: an Observational Mono-centre 8-year Assessment of Outcome
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- Return of spontaneous circulation (ROSC)
研究概览
简要总结
With ethical approvement, the investigators want to assess the incidence, circumstances and outcomes of patients with perioperative cardiac arrests over a period of 8 years.
Currently, there is little data and information about a cardiovascular arrests during anesthesia. Little is also known about the health-related quality of life afterwards. In the investigators research project, the investigators want to find out if there are, for example, specific factors that cause cardiovascular arrests and factors that can improve the chances of survival after a cardiovascular arrest. The investigators are also looking for possible factors and measurements that can minimize or even prevent future events during anesthesia.
详细描述
A perioperative cardiac arrest is a special form of in-hospital cardiac arrest. It was claimed that perioperative cardiac arrests are under-investigated. The spare existing data suggest incidences of perioperative cardiac arrest to be between 0.5 - 3 per 10.000 for adult patients and 2 - 10 per 10.000 for paediatric patients. Data on circumstances, predictors and outcomes of perioperative cardiac arrest are rare, especially for paediatric patients. Some reports suggest that incidence is negatively associated with a country's higher development. As no Swiss data is available on this topic, this retrospective audit aims to bridge the knowledge gap and finally intends to make clinicians aware of potential risks or contributing factors of survival, which might raise safety for all patients undergoing procedures under anaesthesia.
The investigators will include all patients of all ages with a perioperative cardiac arrest at Bern University Hospital from 1st January 2015 until 31st December 2021 (7 year observational period).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •A perioperative cardiac arrest before 1st January 2015 or after 31st December 2021
- •<5 chest compressions (direct, mechanical or extracorporeal Cardiopulmonary Resuscitation (CPR))
- •All in-hospital cardiac arrests, that occur without being under anaesthesia care
- •Patients already admitted to a hospital with a cardiac arrest (out-of hospital cardiac arrests)
结局指标
主要结局
Return of spontaneous circulation (ROSC)
时间窗: 60 minutes
Number of patients with a Return of spontaneous circulation (ROSC) during resuscitation
次要结局
- Sustained ROSC(60 minutes)
- Survival post-anaesthesia care unit or intensive care unit(24 hours)
- SF-12 after hospital discharge(1 month)
- Survival to hospital discharge(4 weeks)
- CPC after hospital discharge(1 month)
- SF-12 3 month after cardiac arrest(3 months)
- CPC 3 month after cardiac arrest(3 months)