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FemPulse Therapy for Overactive Bladder in Women

Not Applicable
Conditions
Urinary Bladder, Overactive
Interventions
Device: FemPulse System
Registration Number
NCT03784170
Lead Sponsor
FemPulse Corporation
Brief Summary

The purpose of this clinical trial is to investigate a new medical device treatment for Overactive Bladder (OAB) in women.

Detailed Description

The FemPulse System is a vaginal ring intended to provide mild electrical stimulation to nerves that regulate bladder function. It is believed that stimulation of these nerves may help relieve the symptoms of OAB.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
21
Inclusion Criteria
  • Females 21 years or older with a diagnosis of Overactive Bladder
  • If of reproductive age, must use a reliable form of contraception
Exclusion Criteria
  • Pregnant, was recently pregnant or is trying to conceive
  • Has a metal pelvic implant or any electrically active implanted medical device
  • Had a previous hysterectomy, pelvic radiation or pelvic cancer
  • Has significant pelvic organ prolapse
  • Had bladder treatment with onabotulinumtoxinA in the previous 12 months
  • Has a significant heart condition

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
TreatmentFemPulse SystemFemPulse System at one device setting
ControlFemPulse SystemFemPulse System at a different device setting
Primary Outcome Measures
NameTimeMethod
All device- and procedure-related adverse events will be collected and tabulatedApproximately 11 days in total

Adverse events

OAB-q - Short FormApproximately 11 days in total

OAB bother quality of life questionnaire

Urinary frequencyApproximately 11 days in total

Frequency of and intervals between urinary voids (voids per day and time between voids)

OAB Symptom ScoreApproximately 11 days in total

OAB symptoms quality of life questionnaire

Urinary urgencyApproximately 11 days in total

Presence or absence of urgency with each void

Urge urinary incontinence (UUI)Approximately 11 days in total

Presence or absence of UUI with each void

Urogenital Distress Inventory - Short FormApproximately 11 days in total

OAB-related distress quality of life questionnaire

Incontinence Impact Questionnaire - Short FormApproximately 11 days in total

Impact of OAB quality of life questionnaire

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (3)

Minnesota Urology

🇺🇸

Woodbury, Minnesota, United States

McKay Urology

🇺🇸

Charlotte, North Carolina, United States

University of Washington Medical Center

🇺🇸

Seattle, Washington, United States

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