A collaborative and international study of bronchiectasis in Indigenous childre

Phase 3

Completed

• Conditions: Bronchiectasis in Indigenous children; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12610000383066
• Lead Sponsor: Menzies School of Health Research

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-05-12
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

Aboriginal, Pacific Islander or Maori children
Aged between 12 months to 8 years (less than 9 years old)
Current resident of study catchment community
At least one episode of pulmonary exacerbation in the last 12 months
No specific cause for bronchiectasis found despite appropriate investigation and hitorical review
Diagnosed with definite bronchiectasis (High resolution CT confirmed) OR a clinical diagnosis of Chronic Supporative Lung Disease after appropriate investigations have been completed (including Full Blood Count, Immunoglobulins and chest Xray)

Exclusion Criteria

Non Indigenous children. Incorrect age. Children who are on long term antibiotic use. Known cause of bronchiectasis such as cystic fibrosis, primary immnunodeficiency, Kartageners syndrome, primary ciliary dyskinesia, Marfans disease, severe burns, aspiration. Is currently undergoing treatment for cancer (having chemotherapy). Post transplant treatment (renal/cardiac and under immunosuppression treatment). Has diabetes. Has central or peripheral nervous system disorder. Has macrolide hypersensitivity. Non resident of study catchment area. Decision made by local doctor (or paediatrician) that long-term antibiotics or long-term placebo are not appropriate at this time.

Study & Design

• Study Type: Interventional
• Study Design: Not specified