Efficacy and safety of Scar Antipruritic cream in the treatment of hypertrophic scar after burn and scald: a randomized controlled trial.
- Conditions
- Hyperplastic scar after burn
- Registration Number
- ITMCTR2000003439
- Lead Sponsor
- Wuxi Third People's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Hypertrophic scar formed after burn and scald for more than 6 months without signs of regression;
2. The scar is raised on the surface of skin, hard and smooth;
3. It has the clinical symptoms of continuous growth, redness, pain and itching, and has no tendency of self-healing and can not subside by itself;
4. The lesions did not exceed the original damage margin, and the boundary was regular. There was no infiltration into the surrounding normal tissues and did not grow like crab feet;
5. Scar length >= 8cm, thickness >= 2mm;
6. Patients who have not received glucocorticoid injection, other laser therapy and other invasive treatment in recent one year;
7. Patients aged 18-55 years, male or female, volunteer;
8. Patients and their families agree and sign the informed consent for special treatment.
1. The lesions are keloid or keloid tendency, such as exceeding the original damage edge, irregular boundary, infiltrating into surrounding normal tissues and growing like crab feet;
2. Pregnant or lactating women;
3. Patients with systemic diseases (liver and kidney insufficiency, cardiopulmonary dysfunction, hyperlipidemia, hypercholesterolemia, anemia, etc.);
4. Patients with serious skin diseases, such as psoriasis, scleroderma, etc;
5. Patients who quit the experiment before the end of treatment, such as death, loss of follow-up, etc.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method VSS;
- Secondary Outcome Measures
Name Time Method Microbiota in scar;VRS;