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Effects of Home-based Mirror Therapy Combined With Task-oriented Training for Patients With Stroke

Not Applicable
Completed
Conditions
Stroke
Interventions
Behavioral: home-based MTOT
Behavioral: hospital-based therapy
Behavioral: hospital-based MTOT
Registration Number
NCT02432755
Lead Sponsor
Chang Gung Memorial Hospital
Brief Summary

The specific aims of this study will be:

1. To compare the immediate and retention treatment effects of the patients receiving home-based mirror therapy combined with task-oriented training (MTOT) with a hospital-based MTOT group and a hospital conventional rehabilitation group on different aspects of outcomes.

2. To examine the feasibility, satisfaction, and safety of this novel home-based MTOT program.

3. To investigate the factors that may affect the efficacy of home-based stroke rehabilitation.

Detailed Description

In this 3-year study project, we will design a single-blind randomized controlled trial (1) to compare the treatment effects of home-based MTOT with a hospital-based MTOT group and a hospital conventional rehabilitation group, (2) to investigate the feasibility, satisfaction, and safety of this home-based program, and (3) to identify the factors that might influence treatment outcomes. An estimated total of 90 patients with stroke will be recruited in this study. All participants will be randomly assigned to receive home-based MTOT or hospital-based rehabilitation for a 4-week training period (a total of 12 sessions). Before the first treatment session, a client-centered questionnaire will be administered to each patient for identifying individual needs and goals. Feasibility evaluation and caregiver's wellbeing will be also assessed. Outcome measures will be conducted at baseline, immediately after treatment, and 3 months follow-up.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3
Inclusion Criteria
  • diagnosed as having a unilateral stroke
  • at least 3 months after stroke onset
  • from 20 to 80 years of age
  • having completed acute rehabilitation care or discharged home
  • a baseline score of the Fugl-Meyer Assessment (FMA) of 20 to 60
  • able to follow the therapy instructions (cognition status will be measured by the Montreal Cognitive Assessment)
  • capable of participating in therapy and assessment sessions.
Exclusion Criteria
  • neglect
  • global or receptive aphasia
  • major medical problems
  • comorbidities that influenced UE usage or caused severe pain

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
home-based MTOThome-based MTOTHome-based mirror therapy combined with task-oriented training (MTOT)
hospital-based therapyhospital-based therapyhospital-based individualized occupational therapy
hospital-based MTOThospital-based MTOThospital-based mirror therapy combined with task-oriented training (MTOT)
Primary Outcome Measures
NameTimeMethod
Change scores of Fugl-Meyer Assessment (FMA)baseline, 4 weeks, 3 months
Change scores of Modified Rankin Scale (mRS)baseline, 4 weeks, 3 months
Secondary Outcome Measures
NameTimeMethod
Change scores of Barthel Index (BI)baseline, 4 weeks, 3 months
Change scores of Box and Block Test (BBT)baseline, 4 weeks, 3 months
Change scores of grip and pinch powerbaseline, 4 weeks, 3 months
Change scores of Revised Nottingham Sensory Assessment (RNSA)baseline, 4 weeks, 3 months
Change scores of Activity monitors (ActiGraph)baseline, 4 weeks, 3 months
Change scores of Stroke Impact Scale (SIS) Version 3.0baseline, 4 weeks, 3 months
Change scores of Motor Activities Log (MAL)baseline, 4 weeks, 3 months
Change scores of Nottingham Extended Activities of Daily Living Scale (NEADL)baseline, 4 weeks, 3 months

Trial Locations

Locations (3)

Taoyuan Chang Gung Memorial Hospital

🇨🇳

Taoyuan, Taiwan

Kaohsiung Chang Gung Memorial Hospital

🇨🇳

Kaohsiung, Taiwan

Taipei Chang Gung Memorial Hospital

🇨🇳

Taipei, Taiwan

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