Working memory training for children who have survived a brain injury

Not Applicable

Completed

• Conditions: Topic: Neurological, Generic Health Relevance and Cross Cutting Themes; Subtopic: Neurological (all Subtopics), Generic Health Relevance (all Subtopics); Disease: Nervous system disorders, Paediatrics; Nervous System Diseases

• Registration Number: ISRCTN01872582
• Lead Sponsor: niversity of East Anglia (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-07-19
• Study Completion: 2017-03-31
• Last Update Posted: 19 March 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 138

Inclusion Criteria

Current inclusion criteria as of 20/02/2018:
Participant inclusion criteria
Potential participants for intervention and placebo group will:
1. Male & female, aged between 8 and 16 years
2. Score at or below the 30th centile on two tasks of verbal WM, listening recall and backward digit recall, from the Automated Working Memory Assessment (AWMA, Alloway, 2007)
3. Be medically stable
4. Be computer literate, and will have access to a computer and the internet
5. Speak English

Participants will have documented evidence of non-progressive ABI, defined as a moderate (Glasgow Coma Scale (GCS) 8 - 12, Post Traumatic Amnesia (PTA 1 - 24 hours) to severe (GCS < 8, PTA > 24 hours) TBI, stroke, herpes encephalitis, and infratentorial tumour with resection or cranial radiotherapy.

Previous inclusion criteria:
Potential participants for intervention and placebo group will:
1. Male & female, aged between 8 and 16 years
2. Score at or below the 30th centile on two tasks of verbal WM, listening recall and backward digit recall, from the Automated Working Memory Assessment (AWMA, Alloway, 2007)
3. Be medically stable
4. Be computer literate, and will have access to a computer and the internet
5. Speak English

For the feasibility/acceptability pilot: participants will have documented evidence of non-progressive ABI, defined as a TBI, stroke, herpes encephalitis, and infratentorial tumour with resection or cranial radiotherapy.

For the full study: participants will have documented evidence of non-progressive TBI and will be survivors of moderate (Glasgow Coma Scale (GCS) 8 ? 12, Post Traumatic Amnesia (PTA 1 ? 24 hours) to severe (GCS < 8, PTA > 24 hours) brain injury.

Exclusion Criteria

Participants will be excluded if:
1. There is evidence of severe damage to organs other than the brain, major medical problems, or the presence of significant mood disturbance.
2. There is evidence of a progressive neurodegenerative condition.
3. There is a pre-morbid history of learning disability or a specific learning impairment affecting working memory (e.g., dyslexia, specific language impairment), conduct disorder, current use of medication impacting on cognition, or a lack of English proficiency.

Study & Design

• Study Type: Interventional
• Study Design: Not specified