Implementation Strategies for a Simple Intervention to Reduce Longterm Benzodiazepine Use in Dutch Community Pharmacies

Not Applicable

Completed

• Conditions: Benzodiazepines Therapeutic Use

• Registration Number: NCT00268775
• Lead Sponsor: Radboud University Medical Center

Brief Summary

The purpose of this study is to compare the effect of two implementation strategies for a simple patient-directed intervention to reduce long-term benzodiazepine use in Dutch community pharmacies.

Detailed Description

In Dutch community pharmacies many projects have been undertaken in the field of pharmaceutical care, with mixed results. It is not yet clear which elements exactly contribute to the success of these projects and to implementation of pharmaceutical care.

One of the subjects to which attention is paid in community pharmacies, is the undesirable long-term use of benzodiazepines. Treatment methods for discontinuation of long-term benzodiazepine use have been studied rather extensively. A simple patient-directed discontinuation letter proved to be effective in several studies.

Comparison: a minimal intervention group (pharmacists carrying out the intervention guided by a manual only) compared to a maximal intervention group (pharmacists receiving a manual, a training aimed at better cooperation and communication with family practitioners and some support in the management of the project).

Study Timeline

• Study Start: 2005-11
• Study First Submitted: 2005-12-21
• Study First Submitted QC: 2005-12-21
• Study First Posted: 2005-12-22
• Primary Completion: 2006-12
• Study Completion: 2006-12
• Status Verified: 2009-08
• Last Update Submitted: 2009-08-17
• Last Update Posted: 2009-08-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20000

Inclusion Criteria

• benzodiazepine use for more than 3 months in the last 12 months AND for more than 60 days in the last 2 months

Exclusion Criteria

• treatment by psychiatrist, treatment of alcohol- or drug misuse, psychotic episodes in history, epilepsy, terminal disease, not mastering the Dutch language, individual criteria used by the family practitioner

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
percentage of general practitioners that reviewed and returned the list of longterm users.
percentage of letters sent by the pharmacists in the four months after receiving the manual.
percentage of long-term benzodiazepine users that managed to quit or significantly reduce their use in months 0-3, 4-6 and 10-12 after receiving the letter.

Secondary Outcome Measures

Name	Time	Method
evaluation of the implementation strategies

Trial Locations

Locations (90)

Apotheek Asten; 🇳🇱 Asten, Netherlands

Apotheek Bakel-Milheeze; 🇳🇱 Bakel, Netherlands

Kring-apotheek Bergeyk; 🇳🇱 Bergeyk, Netherlands

Apotheek Berlicum; 🇳🇱 Berlicum, Netherlands

Lloyds Apotheek van Kollenburg; 🇳🇱 Best, Netherlands

Apotheek de Schakel; 🇳🇱 Best, Netherlands

Apotheek Heivelden; 🇳🇱 Best, Netherlands

Apotheek Blanckenburgh; 🇳🇱 Beuningen, Netherlands

Apotheek Bladel; 🇳🇱 Bladel, Netherlands

Apotheek Bocholtz; 🇳🇱 Bocholtz, Netherlands

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