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Outcomes and quality of life in patients with locally advanced cancers of vulva and vagina.

Not Applicable
Conditions
Health Condition 1: C52- Malignant neoplasm of vaginaHealth Condition 2: C519- Malignant neoplasm of vulva, unspecified
Registration Number
CTRI/2022/01/039262
Lead Sponsor
Tata Memorial Centre
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients diagnosed with vulvo-vaginal cancer.

2. Patients treated with Radiation+/- chemotherapy +/- surgery from January 1, 2019- December 31, 2023.

Exclusion Criteria

1. Patients with Metastatic disease at the presentation.

2. Incomplete information on the EMR.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To report patterns of relapse and disease outcomes in patients with vulvovaginal cancer treated with radiation (+/- chemotherapy): RFS, DFSTimepoint: 3 Years
Secondary Outcome Measures
NameTimeMethod
To report on acute and late effect of treatment outcomes using CTCAE.Timepoint: 5 Years;To report on longitudinal QOL using EORTC QLQ C-30 and VU-34 (English, Hindi, Marathi as applicable)Timepoint: 4,8,12,16,20,24,30,36,42,48, 54,60 months;To report outcomes as a function of p16, AKT, PDL-1 expression.Timepoint: 5 Years
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