Genetic Polymorphysm of Cholesterol 24 S Hydroxylase in Patients With Glaucoma and AMD

Not Applicable

Completed

• Conditions: Glaucoma
• Interventions: Biological: assessing the blood level of cholesterol 24 S hydroxylase

• Registration Number: NCT00629044
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

The aim of this study is to assess the implicitement of the cholesterol 24 S hydroxylase gene and the 24 S hydroxycholesterol in glaucoma and in age related macular degeneration.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-11
• Study First Submitted: 2008-02-25
• Study First Submitted QC: 2008-02-25
• Study First Posted: 2008-03-05
• Status Verified: 2009-08
• Primary Completion: 2009-11
• Study Completion: 2011-01
• Last Update Submitted: 2011-03-25
• Last Update Posted: 2011-03-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 320

Inclusion Criteria

• Patient with Glaucoma
• Patient with AMD
• Healthy patient

Exclusion Criteria

• All patients who use any treatment in order to maintain in normal value their blood cholesterol

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
G	assessing the blood level of cholesterol 24 S hydroxylase	-
AMD	assessing the blood level of cholesterol 24 S hydroxylase	-
Healthy subjects	assessing the blood level of cholesterol 24 S hydroxylase	-

Primary Outcome Measures

Name	Time	Method
To know if cholesterol 24 S hydroxylase and 24 hydroxycholesterol are involve in Glaucoma and AMD	2 years

Trial Locations

Locations (1)

Ophthalmology Unit CHU Dijon; 🇫🇷 Dijon, Burgundy, France