NCT00629044CompletedNot Applicable
Etude du Polymorphysme génétique de la cholestérol 24S Hydroxylase et Des Teneurs en 24S hydroxycholestérol Chez Des Patients Atteints de Glaucome ou de dégénérescence Maculaire liée à l'âge.
Centre Hospitalier Universitaire Dijon1 site in 1 country320 target enrollmentStarted: November 1, 2007Last updated:
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 320
- Locations
- 1
- Primary Endpoint
- To know if cholesterol 24 S hydroxylase and 24 hydroxycholesterol are involve in Glaucoma and AMD
Study Overview
Brief Summary
The aim of this study is to assess the implicitement of the cholesterol 24 S hydroxylase gene and the 24 S hydroxycholesterol in glaucoma and in age related macular degeneration.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Screening
- Masking
- None
Eligibility Criteria
- Ages
- 40 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patient with Glaucoma
- •Patient with AMD
- •Healthy patient
Exclusion Criteria
- •All patients who use any treatment in order to maintain in normal value their blood cholesterol
Arms & Interventions
G
Active Comparator
Intervention: Assessing the blood level of cholesterol 24 S Hydroxylase (Biological)
AMD
Active Comparator
Intervention: Assessing the blood level of cholesterol 24 S hydroxylase (Biological)
Healthy subjects
Active Comparator
Intervention: assessing the blood level of cholesterol 24 S hydroxylase (Biological)
Outcomes
Primary Outcomes
To know if cholesterol 24 S hydroxylase and 24 hydroxycholesterol are involve in Glaucoma and AMD
Time Frame: 2 years
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Completed
Not Applicable
Genetic Polymorphisms, Steatosis and DiabetesType 1 and 2 DiabetesNCT02045563Centre Hospitalier Universitaire Dijon507
Completed
Not Applicable
Gene Analysis and Treatment Optimization in Chinese Homozygous Familial HypercholesterolemiaHomozygous Familial HypercholesterolemiaNCT01878604Central South University5
Completed
Not Applicable
The Genetic, Protein, and Lipid Basis of Variation in Cholesterol EffluxLipid Metabolism DisordersNCT04061018University of Texas Southwestern Medical Center86
Active, not recruiting
Not Applicable
HYPOCHOL : A Genetically-based Strategy to Identify New Targets in Cholesterol MetabolismHypobetalipoproteinemiaNCT02354079Nantes University Hospital435
Active, not recruiting
Phase 1
Heredity and treatment of increased cholesterol concentratioMedDRA version: 14.1Level: LLTClassification code 10020604Term: HypercholesterolemiaSystem Organ Class: 10027433 - Metabolism and nutrition disordershypercholesterolemiaEUCTR2012-001638-33-CZInstitute for Clinical and Experimental Medicine66