Antenatal Diagnosis of Coarctations of the Aorta. Prospective Observational Study.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Search for ultrasound risk factors associated with diagnosis coarctation of the aorta
研究概览
简要总结
Prenatal diagnosis of coarctation is difficult because the ductus arteriosus masks the isthmus narrowing. The problem lies in the fact that it is difficult to assert in utero diagnosis and to predict severity of neonatal symptomatology. However, it is essential to try to establish the diagnosis since it has been shown that the prenatal diagnosis improves survival and reduces morbidity.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •pregnant or having given birth in the last 12 months in one of the participating centers
- •have had an ultrasound screening in the 2nd or 3rd trimester
- •addressed or being addressed to the Pluridisciplinary Center for Prenatal Diagnosis for suspected coarctation of isolated aorta in front of: ventricular asymmetry at the aegis of the left ventricle or the large vessels at the aorta, discovered during a screening ultrasound second or third quarter.
- •be able to understand and follow the ins and outs of the study
- •Have been informed of the study and have not objected to it
排除标准
- •Associated complex cardiac disease (transposition of large vessels, atrioventricular duct, right ventricle with double outlet) with the exception of inter ventricular communications
- •Left ventricular hypoplasia
- •Suspicion of interruption of the aortic arch
结局指标
主要结局
Search for ultrasound risk factors associated with diagnosis coarctation of the aorta
时间窗: 24h after birth
Calculation of sensitivity, specificity and ROC (Receiver Operating Characteristic) curves of the different ultrasound parameters according to post-natal confirma-diagnosis of coarctation of the aorta in order to create a score to improve the antenatal diagnosis of coarctation the aorta.
次要结局
未报告次要终点