Assay for detection of neutralizing antibodies against interferon-beta in multiple sclerosis
Not Applicable
- Conditions
- multiple sclerosis
- Registration Number
- JPRN-UMIN000005797
- Lead Sponsor
- Department of Neurology, Tohoku University School of Medicine
- Brief Summary
5% of the patients with interferon-beta-1a and 10% of the patients with interferon-beta-1b revealed to have high titer of neutralizing antibody and seemed to be influenced to clinical course.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
none
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Analysis of frequency of interferon-beta neutralizing antibody in Japanese patients with multiple sclerosis treated by interferon-beta
- Secondary Outcome Measures
Name Time Method