MedPath

Magnetic Resonance Imaging (MRI) Study of the Hippocampus After Infarction in the Territory of the Middle Cerebral Artery

Conditions
Ischemic Stroke
Registration Number
NCT00867581
Lead Sponsor
Huazhong University of Science and Technology
Brief Summary

The purpose of this study is to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Detailed Description

40 patients with middle cerebral artery infarction and 40 healthy volunteers will be observed. All of them will receive MRI scan and the assessment of the neuropsychological function (MMSE, AVLT, HAMD) intending to observe delayed neuronal death of hippocampus after middle cerebral artery infarction in human beings.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
80
Inclusion Criteria
  • Clinical diagnosis of middle cerebral artery infarction
  • At least six months from the stroke
  • Must be able to measure his(her) neuropsychologic function (by MMSE, AVLT)
Exclusion Criteria
  • Unable to undergo examinations due to disturbances of consciousness or medical conditions
  • Severe dementia, apraxia, disturbances of sensation or perception
  • Serious complications including severe heart failure, hepatic dysfunction, renal insufficiency,or shock
  • Parkinson's disease, malignant tumor, autoimmune diseases

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of Neurology of Tongji Hospital, Huazhong University of Science and Technology

🇨🇳

Wuhan, Hubei, China

© Copyright 2025. All Rights Reserved by MedPath